Digestive Diseases

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So for almost years, doctors prescribed a treatment involving rest and a bland diet. Hordes of intestinal bacteria get to work, releasing a variety of gases in the process, including carbon dioxide, hydrogen, methane and hydrogen sulfide which gives flatulence its rotten-egg stench. It's part of the digestive tract, but it doesn't seem to do anything, though it can cause big problems because it sometimes gets infected and needs to be removed. In the small intestine, the pH becomes crucial; it needs to be finely balanced in order to activate digestive enzymes. Axe on Twitter 22 Dr.

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Patients typically gift with abdominal pain, weight loss, fever, anorexia, modification in gut habits, nausea, and innate reflex.

The identification is commonly delayed and is sometimes created through a mixture of radiologic, endoscopic, microbiologic, histologic, and molecular techniques. Antimicrobial treatment is that the same as for TB.

Surgery is sometimes needed. Constipation occurs when bowel movements become difficult or less frequent. The normal length of time between bowel movements ranges widely from person to person. Some people have bowel movements three times a day; others, only one or two times a week. Going longer than three days without a bowel movement is too long. After three days, the stool or feces become harder and more difficult to pass. People usually sit down with a "stomachache" or "abdominal cramps" to sit down with pain that's perceived anyplace within the abdominal space.

As such, the list of potential causes is extraordinarily varied. Organs of the abdomen embody the abdomen, bowel, colon, liver, bladder, and duct gland, and issues or diseases of all of those organs is also the supply of pain. Digestion of protein begins in this place. The stomach has three main roles. It stores swallowed food.

It mixes the food with stomach acids. Then it sends the mixture to the small intestine. Most people have a problem with their stomach at any time. Indigestion and inflammation are common problems. You can relieve some stomach problems with over-the-counter medicines and lifestyle changes, such as avoiding fatty foods or eating more slowly.

Other problems like peptic ulcers or GERD require medical attention. The most common symptom of a stomach ulcer is a burning or gnawing pain that develops in your abdomen. The pain can also travel up to your neck, down to your navel belly-button or through to your back. The pain associated with a stomach ulcer is caused by the ulcer itself and stomach acid that comes into contact with the ulcer and irritates it. The pain can last from a few minutes to a few hours.

Abdominal bloating is a condition in which the abdomen feels uncomfortably full and tight and may be visibly swollen distended. Bloating is a common complaint, affecting between 10 and 30 percent of adults. Severe abdominal pain and bloating that occur suddenly, especially if you also have nausea and vomiting, may be a sign of a bowel obstruction from scar tissue or a tumor pressing on the bowel.

The glands located in your mouth and throat. The most important secretion glands are the salivary gland, submandibular, and articulator glands. They all secrete saliva into your mouth, the salivary gland through tubes that drain saliva referred to as salivary glands, close to your higher teeth, submandibular beneath your tongue, and therefore the articulator through several ducts within the floor of your mouth.

Besides these glands, there are small glands referred to as minor salivary glands placed in your lips, inner cheek space buccal mucosa , and extensively in alternative linings of your mouth and throat. Home Publications Conferences Register Contact.

Guidelines Upcoming Special Issues. Publication Policies and Ethics. Submit Manuscript Journal Impact Factor 0. About the Journal Index Copernicus Value Next stop for these nutrients: And the leftover waste — parts of the food that your body can't use — goes on to the large intestine.

The nutrient-rich blood comes directly to the liver for processing. The liver filters out harmful substances or wastes, turning some of the waste into more bile.

The liver even helps figure out how many nutrients will go to the rest of the body, and how many will stay behind in storage. For example, the liver stores certain vitamins and a type of sugar your body uses for energy. At 3 or 4 inches around about 7 to 10 centimeters , the large intestine is fatter than the small intestine and it's almost the last stop on the digestive tract. Like the small intestine, it is packed into the body, and would measure 5 feet about 1.

The large intestine has a tiny tube with a closed end coming off it called the appendix say: It's part of the digestive tract, but it doesn't seem to do anything, though it can cause big problems because it sometimes gets infected and needs to be removed.

Like we mentioned, after most of the nutrients are removed from the food mixture there is waste left over — stuff your body can't use. This stuff needs to be passed out of the body. Can you guess where it ends up? Well, here's a hint: It goes out with a flush. Before it goes, it passes through the part of the large intestine called the colon say: CO-lun , which is where the body gets its last chance to absorb the water and some minerals into the blood.

As the water leaves the waste product, what's left gets harder and harder as it keeps moving along, until it becomes a solid. Yep, it's poop also called stool or a bowel movement. The large intestine pushes the poop into the rectum say: REK-tum , the very last stop on the digestive tract. The solid waste stays here until you are ready to go to the bathroom.

When you go to the bathroom, you are getting rid of this solid waste by pushing it through the anus say: There's the flush we were talking about! Abstract Bile acids BAs are not only digestive surfactants but also important cell signaling molecules, which stimulate several signaling pathways to regulate some important biological processes.

Graphical abstract The bile-acid-activated nuclear receptor, farnesoid X receptor FXR , is involved in the pathophysiology of a wide range of diseases of gastrointestinal tract, including inflammatory bowel disease, colorectal cancer and type 2 diabetes. ASBT apical sodium-dependent bile salt transporter. BMI body mass index. BSEP bile salt export pump. DSS dextrane sodium sulfate.

ERK extracellular signal-regulated kinase. FABP6 fatty acid-binding protein subclass 6. FFAs free fatty acids. FGF19 fibroblast growth factor FGFR4 fibroblast growth factor receptor 4. FXR farnesoid X receptor. FXRE farnesoid X receptor response element. GLP-1 glucagon-like peptide 1.

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